Episode Synopsis: A couple undergoes surgery. Derek and Meredith's clinical trial gets a second shot from a new patient. Izzie helps Alex. McSteamy hooks up with someone.
Ellen Pompeo,Sandra Oh,Patrick Dempsey,Katherine Heigl,Sara Ramirez,T.R. Knight,Justin Chambers,Chandra Wilson,Kate Walsh,Eric Dane,Brooke Smith,Chyler Leigh,Kim Raver,Jesse Williams,Sarah Drew,Loretta Devine,Isaiah Washington,James Pickens Jr.,Kevin McKidd,Jessica Capshaw,
Episode Guest Stars
Kathryn Meisle,Jurnee Smollett,Amy Madigan, Marshall Allman,
- Sterling Knight4 Pictures